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. 2023 Jun 8;24(12):9909. doi: 10.3390/ijms24129909

Figure 3.

Figure 3

CD163/CD8 EF ratio correlates with EFS and significantly associates with POD24 event. (a) Representative bright-field IHC images of automated double IHC CD163 (brown) and CD8 (red) staining. Scale bars 200 μm. (b) Box plots of the percentage of CD163/CD8 EF ratio in relation to POD24 event, each dot represents the median value of 10 ROIs for a single patient. (c) High CD163/CD8 EF ratio (≥16.25/HPF; n = 13) showed a worse EFS than those with low values (n = 29). (d–g) Box plots of percentage of CD163/CD8 EF ratio, each dot represents the median value of 10 ROIs for each patient. PD, progressive/recurrent disease; POD24, progression of disease within 24 months; EFS, event-free survival; FLIPI, Follicular Lymphoma international prognostic index; H/I, High/Intermediate; L, Low. Only values statistically significant are reported: * p < 0.05.