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. 2023 Jun 6;24(12):9824. doi: 10.3390/ijms24129824
PHYs Phytochemicals
NPs Nanoparticles
DDSs drug delivery systems
DSs delivery systems
GIT gastrointestinal tract
NSs Nanosuspensions
NEs Nanoemulsions
PETs particle engineering techniques
CH conventional homogenization
HPH high-pressure homogenization
UHPH ultra-high-pressure homogenization
FAs formulation approaches
SD spray drying
SFD spray freeze-drying
SFL spray freezing into liquid
TFF thin film freezing
SFE supercritical fluid extraction
EE encapsulation efficiency
DCs dendritic cells
ABC ATP-binding cassette
N.A. not applicable
N.R. not reported
EA ellagic acid
HLB hydrophilic–lipophilic balance
GRAS generally regarded as safe
B-U bottom-up
T-D top-down
CTNIs combination techniques
CTNO combination technology
MM mechanical method
RES Resveratrol
ATRA all-trans retinoic acid
RSA radical scavenging activity
ORAC oxygen radical absorbance capacity
DL drug loading
NRG naringenin
ROS reactive oxygen species
DLA Dalton lymphoma ascites
GSH glutathione reductase
OA oleanolic acid
HPC-SSL hydroxypropyl cellulose-SSL
PVP-K30 polyinylpyrrolidone-K30
HELF human embryonic lung fibroblast
CSL celastrol
SC supercritical
SC sodium cholate
SLS sodium lauryl sulfate
PEG polyethylene glycol
TPGS D-α-tocopherol polyethylene glycolsuccinate
SGF simulated gastric fluid
PB phosphate buffer
GLA glaucocalyxin A
SEOA sucrose ester-stabilized oleanolic acid
SEDDSs self-emulsifying drug delivery systems
SNEDDSs self-nanoemulsifying drug delivery systems
SMEDDSs self-microemulsifying drug delivery systems
SDEDDSs self-double-emulsifying drug delivery systems
LET low-energy techniques
HET high-energy techniques
MF microfluidization
US ultrasonication
PIT phase inversion temperature
PIC phase inversion composition
SE spontaneous emulsification
EOs essential oils
RO rosmarinic acid
LDL low-density lipoprotein
HDL high-density lipoprotein
PNEs pickering nanoemulsions
CmLN curcumin-loaded lipid NEs
PUFA polyunsaturated fatty acid
OSCC oral squamous cell carcinoma
CUR-NEs curcumin-loaded lipid NEs
EGCG epigallocatechin-3-gallate
ALA α-lipoic acid
PGPR polyglycerol polyricinoleate
TAC total antioxidant capacity
FRAP ferric-reducing antioxidant power
ORAC oxygen radical absorbance capacity
3GIO tri-glycerol monooleate
SML sucrose monooleate
PGPR polyglycerol polyricinoleate
BC bacterial cellulose
WPI whey protein isolate
ESE ethoxylated sorbitan esters
PEGM poly(ethylene glycol) monooleate
3,3-DODOXAP 3,3-dioctadecyloxacarbocyanine perchlorate
DHA docosahexaenoic acid
HSS high-speed shearing
SEO Satureja montana essential oil
PPG polypropylene glycol
MDA-MB-231 cell model of late-stage breast cancer
SMP sucrose palmitate
BCL baicalein
M myricitrin
ITCs isothiocyanates
SFN sulforaphane
AITC allyl isothiocyanate
BITC benzyl isothiocyanate
PEITC phenethyl isothiocyanate
PLGA poly (lactic-glycolic acid)
EFFR epidermal growth factor receptor
CO cerium oxide
MICs minimal inhibitory concentrations
MBCs minimal bactericidal concentrations
KPF kaempferol
KPF-NE KPF-loaded NE
KPF-MNE KPF-loaded mucoadhesive NE
FDA Food and Drug Administration
CDER Center for Drug Evaluation and Research
OTR Office of Testing and Research
GDUFA Generic Drug User Fee Amendments
NRAWG Nanotechnology Risk Assessment Working Group
SLNs solid lipid NPs
JNK c-Jun N-terminal kinase
[P(b-Asp-co-APIA)-PEG] pH-sensitive poly{(benzyl-L-aspartate)-co-[N-(3-aminopropyl) imidazole-L-aspartamide]}-poly(ethylene glycol)
IBD inflammatory bowel disease
RA rheumatoid arthritis
PS-NPs polysaccharide-based nanocarriers
[P(Asp-g-Im)-PEG] poly(aspartic acid-graft-imidazole)-poly(ethylene glycol)
mPEG-PCL mono methoxy poly (ethylene glycol)-poly (e-caprolactone) di-block copolymers
CNTs carbon nanotubes
OS oxidative stress
MWCNTs multiwalled CNTs
EFSA European Food Safety Authority
EMA European Medicine Agency
EEA European Economic Area
QWP Quality Working Party
SLNPs solid lipid NPs
PVA polyvinyl alcohol
PNIPAM poly(N-isopropylacrylamide)
PCB poly(carboxybetaine)
PSB poly(sulfo-betaine)
SWCNTs single-walled carbon nanotubes
NC nanocomposite
FSP flame spray pyrolysis
CAPs clinically applied phytochemicals