Table 2.

Serum biochemical parameters in all experimental groups.

Biochemical Parameters	Control	ERFE 300 mg/ kg	Diclofenac 50 mg/kg	ERFE + Diclo	Reference Values [25]
GLU mmol/L	6.39 ± 0.12	7.1 ± 0.42	6.5 ± 0.41	7.8 ± 0.29	6.9–11.3
Urea mmol/L	3.68 ± 0.32	3.8 ± 0.36	4.8 ± 0.22 *	4.6 ± 0.22	3.3–6.8
Creat µmol/L	34.1 ± 12.3	32.3 ± 12.8	35.1 ± 16.2	39.2 ± 12.6	29–81
TP g/L	63.7 ± 3.2	62.2 ± 4.6	62.5 ± 5.3	59.2 ± 3.3	53–63
ALB g/L	28 ± 1.3	28.2 ± 1.2	26.1 ± 2.2	27.4 ± 3.1	26–29
ASAT U/L	86.6 ± 4.1	86.1 ± 5.4	121.3 ± 3.8 *	98.2 ± 4.8	70–155
ALAT U/L	35.2 ± 4.2	37.6 ± 6.1	42.2 ± 4.3	38.4 ± 3.6	35–39
AP U/L	198.3 ± 9.2	162.4 ± 5.3	189.8 ± 6.3	162.4 ± 9.2	62–230
GGT U/L	2.2 ± 0.2	3.2 ± 0.6	5.6 ± 0.3 *	5.8 ± 0.6 *	0.3–6.9
AMYL U/L	599.7 ± 18.2	632.2 ± 26.6	568 ± 12.3	492.3 ± 22.6	485–1942
T-Bil µmol/L	4.4 ± 0.48	4.0 ± 0.28	7.4 ± 0.42 *+	4.3 ± 0.38	1.7–6.8
D-Bil µmol/L	3.6 ± 0.86	3.5 ± 0.84	6.4 ± 0.56 *	3.9 ± 0.24	0–6.8
Chol mmol/L	1.1 ± 0.06	2.0 ± 0.09	1.6 ± 0.06	1.7 ± 0.04	1.5–2.1
TRIG mmol/L	0.38 ± 0.001	0.42 ± 0.003	0.66 ± 0.006 *	0.65 ± 0.004 *	1.1–1.2
UA mmol/L	42.6 ± 1.4	38.5 ± 2.3	43.3 ± 3.3	41.9 ± 2.3	30–262

* p < 0.05 vs. control group; ⁺ p < 0.05 vs. reference range.