Table 4.
Gene | SNP rs Number | Genotype | Male | Allele Frequency in Males | Female | Allele Frequency in Females | p Value |
---|---|---|---|---|---|---|---|
ABCB1 | rs4148738 | CC | 21 (23.3) | C:T = 0.43: 0.57 | 11 (18.3) | C:T = 0.42:0.57 | 0.57 |
CT | 36 (40.0) | 29 (48.3) | |||||
TT | 33 (36.7) | 20 (33.3) | |||||
C | 78 | 51 | |||||
T | 102 | 69 | |||||
ABCB1 | rs1045642 | AA | 22 (24.4) | A:G = 0.46:0.54 | 11 (18.3) | A:G = 0.45:0.55 | 0.49 |
AG | 39 (43.3) | 32 (53.3) | |||||
GG | 29 (32.2) | 17 (28.3) | |||||
A | 83 | 54 | |||||
G | 97 | 66 | |||||
ABCB1 | rs2032582 | CC | 34 (37.8) | C:A = 0.53:0.47 | 19 (31.7) | C:A = 0.52:0.48 | 0.53 |
CA | 28 (31.1) | 24 (40.0) | |||||
AA | 28 (31.1) | 17 (28.3) | |||||
C | 96 | 62 | |||||
A | 84 | 58 | |||||
ABCB1 | rs1128503 | AA | 33 (36.7) | A:G = 0.55:0.45 | 20 (33.3) | A:G = 0.57:0.43 | 0.46 |
AG | 33 (36.7) | 28 (46.7) | |||||
GG | 24 (26.7) | 12 (20.0) | |||||
A | 99 | 68 | |||||
G | 81 | 52 | |||||
CES1 | rs8192935 | AA | 33 (36.7) | A:G = 0.63:0.37 | 22 (36.7) | A:G = 0.61:0.39 | 0.78 |
AG | 47 (52.2) | 29 (48.3) | |||||
GG | 10 (11.1) | 9 (15.0) | |||||
A | 113 | 73 | |||||
G | 67 | 47 | |||||
CES1 | rs2244613 | GG | 20 (22.2) | G:T = 0.47:0.53 | 17 (28.3) | G:T = 0.48:0.52 | 0.48 |
GT | 45 (50.0) | 24 (40.0) | |||||
TT | 25 (27.8) | 19 (31.7) | |||||
G | 85 | 58 | |||||
T | 95 | 62 | |||||
CES1 | rs71647871 | GG | 88 (97.8) | G:A = 0.99:0.01 | 60 (100.0) | G:A = 1.00:0.00 | 0.52 |
GA | 2 (2.2) | 0 | |||||
AA | 0 | 0 | |||||
G | 178 | 120 | |||||
A | 2 | 0 |
Note: p value of Hardy–Weinberg equilibrium test.