Table 2.

Significant difference in cell subclusters in aHUS and healthy controls.

Significantly Increased Immune Cell Subclusters in aHUS Patients Compared to Healthy Controls with Correlated Gene Expression Increasing
Cell Subclusters		p value	Higher expression levels of gene
Classical monocyte subclusters 6		p < 0.01	RPS27
Classical monocyte subclusters 7		p < 0.05	IFI27
Central memory CD8 T-cells subcluster 3		p < 0.05	CXCR4
Non-Vd2 gd T-cells subcluster 4		p < 0.05	SYNE2
Th1 cells subcluster 3		p < 0.05	MT-CYB
Th17 cells subcluster 4		p < 0.05	MT-ATP6
Significantly Increased Immune Cell Subclusters in Healthy Controls Compared to aHUS Patients with Correlated Gene Expression Increasing
Cell Subclusters		p value	Higher expression levels of gene
Central memory CD8 T-cells subcluster 1		p < 0.05	EIF3E
Th1 cells subcluster 0		p < 0.05	RPS27
Non classical monocytes subcluster 5		p < 0.01	LYPD2
Terminal effector CD4 T-cells subcluster 3		p < 0.01	KLRD1
Th17 cells subcluster 3		p < 0.05	ACTG1, CD52 and LGALS1