Table 3.

Significant difference in cell subclusters in aHUS disease activity.

Significantly Increased Immune Cell Subclusters in Unstable aHUS Patients Compared to Stable aHUS Patients with Correlated Gene Expression Increasing
Cell Subclusters		p value	Higher expression levels of gene
Classical monocyte subclusters 4		p < 0.05	NEAT1, MT-ATP6 and MT-CYB
Central memory CD8-T cells subcluster 2		p < 0.05	VIM
Non-Vd2 gd T-cells subcluster 1		p < 0.05	ACTG1
Terminal effector CD8—cells subcluster 3		p < 0.05	RPL13
Terminal effector CD8 T-cells subcluster 5		p < 0.01	KLRB1
Significantly Increased Immune Cell Subclusters in stable aHUS Patients Compared to unstable aHUS Patients with Correlated Gene Expression Increasing
Cell Subclusters		p value	Higher expression levels of gene
Central memory CD8 T-cells subcluster 1		p < 0.05	RPL23
Non-Vd2 gd T-cell subcluster 0		p < 0.05	GZMH
Th1 cells subcluster 0		p < 0.05	RPS27, RPS4X