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. 2023 Jun 19;20(12):6178. doi: 10.3390/ijerph20126178

Table 1.

Some features associated with polypharmaceutical UK hospital admissions.

Medicine Measures Risk Rate Consequence Treatment Duration (Months) Age (Years)
2 or more medicines with moderate 97 Confusion N/A >18
or high anticholinergic activity 8 Fracture
1 or more medicines for dementia + 1 or more medicines with moderate or high 316 Confusion N/A >18
anticholinergic activity 53 Fracture
NSAID + RAS + diuretic 16 Kidney Injury N/A >18
Z-drug for more than one month 162 Fall > 1 >65
28 Fracture
benzodiazepine for more than one month 181 Fall > 1 >65
32 Fracture
benzodiazepine and Z-drug (not concurrently) 212 Fall >1 >65
for more than one month 35 Fracture
NSAID without gastro-protection 9 bleed N/A >65
NSAID + oral anticoagulant 33 bleed N/A >18
oral anticoagulant + anti-platelet without gastro-protection 31 bleed N/A >18
aspirin + anti-platelet without gastro-protection 20 bleed N/A >18
oral or transdermal opioid without a laxative 8 constipation N/A >18
oral or transdermal opioid for more than three months 18 respiratory depression, overdose poisoning or confusion >3 >18
inhaled Long Acting Beta-agonist (LABA) without an inhaled corticosteroid (ICS) 9 exacerbation of asthma N/A N/A