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The selected potential molecular drugs based on their regulatory ability, toxicity, sensitivity, and their binding of drug targets for the therapeutic treatment of psoriasis.
| Target | FOXO1 | NF-kB | STAT3 | CEBPB | ERK1/2 | Toxicity (LC50) |
Sensitivity (PRISM) |
|
|---|---|---|---|---|---|---|---|---|
| Drug | ||||||||
| Betulinic acid | ● | ● | ● | 6.712 | −0.103441 | |||
| Butein | ● | ● | 5.776 | −0.054450 | ||||
| naringin | ● | ● | ● | 6.921 | 0.132488 | |||
| Chemical structure of multiple molecules drug | ||||||||
| Betulinic acid | Butein | naringin | ||||||
|
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