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URB878 decreased bleomycin-induced fibrosis. (A) Sham, (B) bleomycin, and (C) bleomycin+URB878 5 mg/kg; (D) soluble collagen; (E) Western blot and relative densitometric analysis of α-SMA and TGF-β. The photos are demonstrative of at least three experiments carried out on different experimental days. The data are expressed as the mean ± SEM of n = 6 animals for each group. *** p < 0.001 vs. sham; # p < 0.05 vs. bleomycin; ### p < 0.001 vs. bleomycin.
