aCL |
anti-cardiolipin antibody |
Akt |
protein kinase B derived from AKR mouse thymoma |
ANA |
anti-nuclear antibody |
APRIL |
a proliferation-inducing ligand |
BAFF |
B cell activating factor of TNF Family |
BAFF-R |
receptor for BAFF |
BCMA |
B cell maturation antigen |
BR3 |
BLyS receptor 3 |
C1q |
Q fragment of complement component 1 |
CCL |
C-C chemokine Receptor |
CCR |
receptor of cysteine-cysteine motif containing chemokine |
CD |
cluster of differentiation |
circRNA |
circular ribonucleic acid |
CKD |
chronic kidney disease |
CSF |
colony stimulating factor |
CXC |
cysteine-X amino acid-cysteine motif containing chemokine |
CXCL |
ligand for CXC chemokine |
DAMP |
damage associated molecular pattern |
DC |
dendritic cell |
DEPs |
differential expressed proteins |
dsDNA |
double-stranded deoxyribonucleic acid |
EC |
endothelial cell |
ECM |
extracellular matrix |
Erb-B |
receptor tyrosine kinase derived from epidermal growth factor |
ESRD |
end-stage renal disease |
EZH-2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
Fab |
a and b fragment of immunoglobulin |
Fc |
c (or constant) fragment of immunoglobulin |
Fh2 |
type II follicular helper T cell |
GMC |
glomerular mesangial cell |
GN |
glomerulonephritis |
HIF |
hypoxia inducible factor |
HLA-DR |
R chain of human leukocyte antigen-class D |
HRMC |
human renal mesangial cell |
IC |
immune complex |
IFN |
interferon |
IFN-I |
type I interferon |
Ig |
immunoglobulin |
IL |
interleukin |
IL-22BP |
interleukin 22 binding protein |
iNOS |
inducible nitric oxide synthase |
IP-10 |
Interferon gamma-induced protein 10 (=CXCL10) |
ISG |
interferon stimulated gene |
ISN |
International Society of Nephrology |
IVIG |
intravenous immunoglobulin G infusion |
JAK |
Janus kinase |
JSLE |
juvenile systemic lupus erythematosus |
KC |
keratinocyte-derived cytokine (=CXCL1) |
LAIR1 |
leukocyte-associated immunoglobulin-like receptor 1 |
LCN-2 |
lipocalin 2 |
LN |
lupus nephritis |
LNA |
locked nucleic acid |
lncRNA |
long non-coding RNA |
LPS |
lipopolysaccharide |
LRR |
leucine rich repeat |
MC |
mesangial cell |
MCP-1 |
monocyte chemoattractant protein 1 |
M-CSF |
myeloid colony stimulating factor |
mDC |
myeloid dendritic cell |
MHC-II |
major histocompatibility complex Class II |
miR |
microRNA |
MPAA |
mycophenolic acid analogue |
MPGN |
membrano-proliferative glomerulonephritis |
mRNA |
messenger ribonucleic acid |
mTOR |
mechanistic target of rapamycin |
ncRNAs |
non-coding RNAs |
NETs |
neutrophil extracellular traps |
NF-kB |
nuclear factor kappa-light-chain-enhancer of activated B cell |
NGAL |
neutrophil gelatinase-associated lipocalin |
NLR |
NOD-like receptor |
NLRP3 |
nucleotide-binding domain leucine-rich repeat (NLR) and pyrin domain-containing receptor 3 |
NMDAR |
N-methyl-D-aspartate receptor |
NOD |
nucleotide-binding oligomerization domain-containing protein |
PAMP |
Pathogen-Associated Molecular Pattern |
PBL |
peripheral blood lymphocyte |
PBMC |
peripheral blood mononuclear cell |
pcDNA |
mammalian expressing vector |
pDC |
plasmacytoid dendritic cell |
PI3K |
phosphoinositide 3 kinase |
PMN |
polymorphonuclear leukocyte |
PRR |
pattern recognition receptor |
RIG-1 |
retinoic acid-inducible gene 1 |
RIP3 |
receptor-interacting serine–threonine kinase 3 |
RLR |
retinoic acid-inducible gene 1 like receptor |
RMC |
rodent glomerular mesangial cell |
RRP8 |
ribosomal RNA-processing protein 8 |
RT-PCR |
reverse transcriptase assisted polymerase chain reaction |
SCF |
stem cell factor |
ScRNA-Seq |
single-cell analysis of RNA sequence |
SIA |
sialic acid |
SLE |
systemic lupus erythematosus |
SLEDAI |
systemic lupus erythematosus disease activity index |
sncRNA |
short non-coding ribonucleic acid |
SOCS |
suppressor of cytokine signaling |
STAT |
signal transducer and activators of transcription |
TACI |
transmembrane activator and calcium modulator and cytophilin ligand interactor |
TCR |
T cell receptor |
TEC |
tubular epithelial cell |
TGF-β |
transforming growth factor beta |
Th |
T helper cells |
THP |
Tamm-Horsfall glycoprotein |
TLR |
toll-like receptor |
TLS |
tertiary lymphoid structure |
TNF-a |
tumor necrosis factor |
TNP-1 |
Spermatid nuclear transition protein 1 |
TPL |
triptolide |
tRNA |
transfer ribonucleic acid |
tsRNA |
tRNA derived small RNA |
Tyk |
tyrosine kinase |
UTR |
untranslated region |
UV |
ultraviolet |
VCAM-1 |
vascular cell adhesion molecule 1 |