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. 2023 Jun 8;24(12):9896. doi: 10.3390/ijms24129896

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Figure 8. Irisin treatment increases the expression of Haptoglobin in the skeletal muscle of Ovx mice. (a) Quadriceps weight normalized to total body weight in Sham-veh (n = 8), Ovx-veh (n = 7) and Ovx-irisin (n = 6) mice. Quantification of mRNA expression for (b) Tfam in quadriceps harvested from Sham-veh (n = 4), Ovx-veh (n = 5) and Ovx-irisin (n = 6) mice and (c) Haptoglobin in quadriceps harvested from Sham-veh (n = 5), Ovx-veh (n = 4) and Ovx-irisin (n = 5) mice. A one-way ANOVA with Tukey’s multiple comparisons tests was performed in a. Kruskal–Wallis with Dunn’s multiple comparison tests was performed in (b,c). Data are presented as box-and-whisker plots with median and interquartile ranges, from max to min, with all data points shown. * p < 0.05 vs. Sham-veh, ## p < 0.01 vs. Ovx-veh.