Table 2.
Coronary Angiography Findings.
| Non/Mild Calcification (n = 171) | Moderate/Severe Calcification (n = 94) | p | Matched Non/Mild Calcification (n = 81) | Matched Moderate/Severe Calcification (n = 72) | p | |
|---|---|---|---|---|---|---|
| Artery | 0.879 | 0.616 | ||||
| LAD | 68.42% (117) | 70.21% (66) | 0.763 | 67.90% (55) | 75.00% (54) | 0.333 |
| LCX | 11.11% (19) | 11.70% (11) | 0.884 | 9.88% (8) | 8.33% (6) | 0.741 |
| RCA | 19.30% (33) | 18.09% (17) | 0.809 | 22.22% (18) | 16.67% (12) | 0.388 |
| Left Main | 0.58% (1) | 0% (0) | 0.458 | 0% (0) | 0% (0) | N/A |
| Ramus | 0.58% (1) | 0% (0) | 0.458 | 0% (0) | 0% (0) | N/A |
| AHA/ACC Classification | 0.010 | 0.374 | ||||
| A | 1.17% (2) | 0% (0) | 0.293 | 1.23% (1) | 0% (0) | 0.344 |
| B1 | 14.04% (24) | 5.32% (5) | 0.030 | 12.35% (10) | 5.56% (4) | 0.146 |
| B2 | 49.12% (84) | 40.43% (38) | 0.174 | 41.98% (34) | 44.44% (32) | 0.758 |
| C | 35.67% (61) | 54.26% (51) | 0.003 | 44.44% (36) | 50.0% (36) | 0.492 |
| TIMI Grade | 0.091 | 0.398 | ||||
| TIMI-0 | 4.68% (8) | 2.13% (2) | 0.297 | 4.94% (4) | 2.78% (2) | 0.492 |
| TIMI-1 | 11.11% (19) | 10.64% (10) | 0.906 | 7.41% (6) | 12.50% (9) | 0.290 |
| TIMI-2 | 21.05% (36) | 10.64% (10) | 0.032 | 18.52% (15) | 11.11% (8) | 0.201 |
| TIMI-3 | 63.16% (108) | 76.60% (72) | 0.025 | 69.14% (56) | 73.61% (53) | 0.542 |
| Total Occlusion | 4.09% (7) | 6.38% (6) | 0.409 | 4.94% (4) | 8.33% (6) | 0.396 |
| Chronic total occlusion | 3.51% (6) | 5.32% (5) | 0.480 | 3.70% (3) | 6.94% (5) | 0.369 |
| Ostium Lesion | 1.75% (3) | 2.13% (2) | 0.831 | 2.47% (2) | 2.78% (2) | 0.905 |
| QCA Analysis | ||||||
| Lesion Diameter (mm) | 1.03 ± 0.38 | 0.95 ± 0.37 | 0.094 | 0.97 ± 0.37 | 0.94 ± 0.38 | 0.611 |
| Lesion Reference Diameter (mm) | 2.94 ± 0.59 | 2.67 ± 0.63 | 0.001 | 2.91 ± 0.58 | 2.70 ± 0.63 | 0.049 |
| Diameter Stenosis (%) | 66.23 ± 12.76 | 66.85 ± 14.02 | 0.718 | 67.66 ± 13.96 | 68.17 ± 14.86 | 0.828 |
| Lesion Area (mm2) | 0.82 (0.43,1.24) | 0.70 (0.35,1.13) | 0.157 | 0.74 (0.38,1.11) | 0.62 (0.32,1.16) | 0.603 |
| Lesion Reference Area (mm2) | 6.45 (5.20,8.49) | 5.50 (3.98,7.23) | 0.001 | 6.27 (5.20,7.37) | 5.70 (3.88,7.26) | 0.077 |
| Area Stenosis (%) | 87.98 ± 7.76 | 87.07 ± 7.97 | 0.931 | 87.61 ± 8.20 | 87.69 ± 8.28 | 0.956 |
| Lesion Length (mm) | 23.95 ± 8.56 | 27.30 ± 9.94 | 0.005 | 24.83 ± 9.12 | 27.16 ± 9.18 | 0.132 |
| Proximal Mean Diameter (mm) | 3.28 ± 0.56 | 3.04 ± 0.60 | 0.002 | 3.25 ± 0.54 | 3.08 ± 0.61 | 0.072 |
| Lesion Mean Diameter (mm) | 2.30 ± 0.47 | 2.10 ± 0.44 | 0.001 | 2.24 ± 0.43 | 2.14 ± 0.44 | 0.160 |
| Distal Mean Diameter (mm) | 2.92 ± 0.64 | 2.75 ± 0.69 | 0.047 | 2.89 ± 0.64 | 2.76 ± 0.72 | 0.257 |
| Proximal Mean Area (mm2) | 3.27 ± 0.65 | 3.10 ± 0.64 | 0.049 | 3.28 ± 0.58 | 3.15 ± 0.66 | 0.212 |
| Lesion Mean Area (mm2) | 2.31 ± 0.49 | 2.12 ± 0.45 | 0.003 | 2.27 ± 0.45 | 2.16 ± 0.45 | 0.178 |
| Distal Mean Area (mm2) | 2.95 ± 0.77 | 2.84 ± 0.84 | 0.288 | 2.99 ± 0.89 | 2.89 ± 0.90 | 0.503 |
| Plaque Symmetry | 0.70 (0.49,0.87) | 0.67 (0.56,0.82) | 0.856 | 0.76 (0.50,0.87) | 0.65 (0.56,0.81) | 0.211 |
| Plaque Area (mm2) | 13.44 (9.95,18.75) | 13.53 (10.25,18.65) | 0.766 | 13.79 (9.77,20.15) | 12.97 (10.35,18.14) | 0.592 |
Abbreviations: LAD = Left Anterior Descending, LCX = Left Circumflex, RCA = Right Coronary Artery, AHA/ACC = American Heart Association/American College of Cardiology, TIMI = Thrombolysis In Myocardial Infarction, QCA = Quantitative Coronary Angiography.