Table 2.
First author and year of publication, PICOS information, and oral manifestation reported in the 8 articles that report atrophic glossitis or geographic tongue among the manifestations of CD.
| Authors | Study Design | No. of Patients/ Controls |
Age Patients/ Controls |
Sex Patients/ Controls |
Diagnosis | Outcome No. (%) |
|---|---|---|---|---|---|---|
| Bramanti et al. (2014) [24] | Cross-sectional | 50/ 54 |
7.5 ± 4.4/ 8.8 ± 2.9 |
22M;28F 22M;32F |
CD | 5 (10%)/2 (3.7%) geographic tongue; 7 (14%)/1 (1.85%) atrophic glossitis |
| Campisi et al. (2007) [26] | Case-control | 197/ 413 |
19.09 (2–75)/ (2–77) |
73M;124F 163M;250F |
CD | 31 (16%)/1 (0.2%) atrophic glossitis; 14 (7%)/5 (1%) geographic tongue |
| Lähteenoja et al. (1998) [33] | Cross-sectional | 136/ 30 |
46.9 ± 9.8/ 47.9 ± 14.3 |
15M;15F 11M;19F |
CD | 4/1 atrophic tongue |
| Ludovichetti et al. (2022) [35] | Retrospective cohort |
38/ 38 |
(6 to 14) | 11M;27F 12M;26F |
CD | 8 (21%)/1 (26%) atrophic glossitis; 7 (18.4%)/3 (7.9%) geographic tongue |
| Macho et al. (2019) [36] | Case-control | 80/ 80 |
13.3 (6 to 18) | 32M;48F 35M;45F |
CD | 6 (7.5%)/1 (1.3%) geographic tongue; 5 (6.3%)/0 (0%) atrophic glossitis |
| Nota et al. (2020) [40] | Structured questionnaire (survey) |
237 | (15 to 56) | 55M;182F | CD | 12 (5.06%) glossitis |
| Procaccini et al. (2007) [41] | Case-control | 50/ 50 |
(3 to 25) | CD | 4 (8%)/1 (2%) atrophic glossitis | |
| Zoumpoulakis et al. (2019) [11] | Case-control | 45/ 45 |
10.3 ± 4.1 10.3 ± 4.05 |
15M;30F | CD | 0 (0%)/0 (0%) atrophic glossitis; 3 (6.7%)/0 (0%) geographic tongue |