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. 2023 Jun 14;24(12):10118. doi: 10.3390/ijms241210118

Table 7.

Comparison of results obtained by qPCR and by dPCR to investigate ABL1 mutations.

T315I
Patient ID Sample ID qPCR dPCR %BCR::ABL1 (IS) Treatment
Patient 1 Sample 1 WT WT 0.054 Nilotinib
Sample 2 T315I T315I 100
Patient 2 Sample 1 WT WT 22.92 BMT
Sample 2 WT T315I NA
Patient 3 Sample 1 WT T315I 0.281 BMT
Patient 4 Sample 1 WT T315I 0.315 Dasatinib
Patient 5 Sample 1 WT T315I 8.9 Dasatinib
Patient 6 Sample 1 WT T315I 1,38 Imatinib
E255K
Patient ID Sample ID qPCR dPCR %BCR::ABL1 (IS) Treatment
Patient 7 Sample 1 WT WT 61.12 Imatinib
Sample 2 WT E255K 72.7
Sample 3 E255K E255K 80.6
Sample 4 WT WT 8.19 Dasatinib
V359F
Patient ID Sample ID qPCR dPCR %BCR::ABL1 (IS) treatment
Patient 8 Sample 1 WT WT 47.3 None
Sample 2 V359F V359F 43.2 Nilotinib

Wt represents “wild-type”; BMT “Bone marrow transplantation”; and NA “Not available”.