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Flowchart showing the potential use of sST2 in chronic heart failure. sST2 is a biomarker of myocardial fibrosis and ventricular remodeling. It could be used in the risk stratification process in addition to NPs and hs-cTnT, as they reflect diverse biologic pathways in HF. Serial testing of sST2 could be helpful in identifying patients who most benefit from anti-remodeling therapies.
