Figure 3.

The neutrophil in tissue repair. Neutrophils upregulate the expression of several cytokines and chemokines that will lead to the recruitment of other immune cells, promote angiogenesis through the release of growth factors, activate fibroblasts and keratinocytes by cytokine production and influence tissue repair via secretion of uPA. (IL: interleukin; TNF: tumor necrosis factor; MCP: monocyte chemotactic protein; VEGF: vascular endothelial growth factor; FGF: fibroblast growth factor; TGF: transforming growth factor; uPA: urokinase-type plasminogen activator).