Figure 8.

Attenuation of oxidative stress-induced mitochondrial respiratory dysfunction by R-EXO. (A) Mitochondrial OCR of A549, ρ⁰ cells, ρ⁰ + REC, ρ⁰ + REC^(R-EXO), and ρ⁰ + REC^(M-EXO) was measured using the Mito Stress kit (n = 3). The order of oligomycin, FCCP, and AA/Rot injections is given. Basal respiration (B), ATP production (C), maximal respiration (D), and spare capacity (E) were analyzed for each group of cells (n = 3). Values represent the mean ± standard deviation of data from three independent experiments. ns, not significant. * p < 0.05, ** p < 0.01, *** p < 0.001.