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. 2023 Jun 12;12(12):3988. doi: 10.3390/jcm12123988

Table 1.

The relationship between the location of the lesion and sexual dysfunctions.

Brain Lesions Sexual Dysfunction
Medial frontal cortex Erectile dysfunction, hyposexuality
Temporal cortex Hypersexuality
Parietal lobe
  • Right

  • Left inferior lobule

Altered cognitive arousal (neglect)
Altered cognitive arousal (reduced sensory awareness)
Anterior cingulate cortex Erectile dysfunction
Insula and claustrum Altered motivational arousal
Erectile dysfunction
Amygdala Anhedonia, altered autonomic arousal
Bilateral damage could lead to hypersexuality (e.g., Kluver–Bucy syndrome)
Hypothalamus Erectile dysfunction
Ejaculatory disorders (sometimes)
Thalamus Erectile dysfunction
Nucleus accumbens Altered motivational arousal
Left basal ganglia Decreased libido
Mesodiencephalic tegmentum Anhedonia
Cerebellum Altered autonomic arousal
Ejaculatory disorders
Anhedonia
Altered emotional arousal
Ejaculatory disorders (left lesion)