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. 2023 Jun 7;12(12):3897. doi: 10.3390/jcm12123897

Table 1.

Demographics of the patients and risk factors associated with delirium (total n = 327). Bold: Risk factors for delirium.

Characteristic,
n (%) Unless Specified Otherwise
Total (n = 327) No Delirium (n = 146) Delirium (n = 181) p
Age (IQR), years 71 (66–78) 68 (64–74) 74.5 (67–80) <0.01
Men (n) 165 (50.5%) 78 (53.4%) 87 (48.1%) 0.261
Risk factors
COVID-19 20 (6.1%) 4 (2.7%) 16 (8.8%) 0.02
Pre-existing cognitive function 75 (22.94%) 11 (7.5%) 64 (35.4%) <0.01
Impaired functional ability 197 (60.2%) 62 (42.5%) 135 (74.6%) <0.01
Physicals restrain 6 (1.8%) 0 6 (3.3%) 0.035
Depression 18 (5.5%) 7 (4.8%) 11 (6.1%) 0.595
History of drug and alcohol abuse 14 (4.3%) 8 (5.5%) 6 (3.3%) 0.349
History of surgery or anesthesia during admission 77 (23.7%) 30 (20.5%) 47 (26.0%) 0.229
Anemia 192 (58.9%) 70 (47.9%) 122 (67.4%) <0.01
Urinary catheterization 166 (50.8%) 46 (31.5%) 120 (66.2%) <0.01
Dehydration 178 (54.4%) 49 (33.5%) 129 (71.3%) <0.01
Constipation 132 (40.50%) 53 (36.3%) 79 (43.6%) 0.165
Impaired sensation (e.g., vision and hearing) 101 (31.2%) 34 (23.3%) 67 (37.0%) <0.01
Mechanical ventilation 82 (25.1%) 34 (23.3%) 48 (26.5%) 0.463
Pain 69 (21.2%) 33 (22.6%) 36 (19.9%) 0.585
Organ failure 210 (65.0%) 85 (58.2%) 125 (69.1%) 0.030
Electrolytes disturbances 240 (73.6%) 88 (60.3%) 152 (84.0%) <0.01
History of sleep deprivation 35 (10.7%) 11 (7.5%) 24 (13.3%) 0.086
Multiple comorbidities (≥3) 279 (85.3%) 115 (78.7%) 164 (90.6%) <0.01
Use of medications known to precipitate delirium 267 (81.9%) 106 (72.6%) 161 (89.0%) <0.01
Polypharmacy (≥5) 306 (93.6%) 129 (88.4%) 177 (97.8%) <0.01