Table 6.
Effect of haplotypes (H) significantly associated with triacylglycerol (TG), high-density lipoprotein cholesterol (HDL-C) levels, and HDL subfractions (in mmol/L). All analyses were adjusted for ethnicity, sex, age, BMI, fasting glucose levels, and current smoking status.
| H1 | H5 | H7 | H8 | |
|---|---|---|---|---|
| rs1532624 | A | C | A | C |
| rs5882 | G | A | A | G |
| rs708272 | A | G | A | G |
| rs7499892 | C | T | C | T |
| rs9989419 | G | A | A | G |
| β (95%CI) | ||||
| TG | Ref. | 0.43 (0.16–0.69) p = 0.002 ** |
N.S. | N.S. |
| HDL-C | Ref. | −0.12 (−0.20–−0.04), p = 0.004 ** |
N.S. | N.S. |
| HDL-1 | Ref. | N.S. | N.S. | −0.02 (−0.04–−0.00) p = 0.030 * |
| HDL-2 | N.S. | N.S. | N.S. | |
| HDL-3 | N.S. | −0.04 (−0.08–−0.01) p = 0.024 * |
N.S. | |
| HDL-4 | N.S. | N.S. | N.S. | |
| HDL-5 | N.S. | −0.01 (−0.02–0.00) p = 0.020 * |
N.S. | |
| HDL-6 | −0.03 (−0.04–−0.01) p = 0.003 ** |
N.S. | N.S. | |
| HDL-7 | −0.01 (−0.02–0.00) p = 0.002 ** |
N.S. | −0.01 (−0.03–0.00) p = 0.019 * |
|
| HDL-8 | −0.01 (−0.02–0.00) p = 0.001 ** |
N.S. | −0.01 (−0.02–0.00) p = 0.012 * |
|
| HDL-9 | −0.01 (−0.01–0.00) p = 0.019 * |
N.S. | N.S. | |
| HDL-10 | N.S. | N.S. | N.S. | |
| Large HDL | Ref. | N.S. | N.S. | N.S. |
| Interm. HDL | −0.05 (−0.09–−0.02) p = 0.008 * |
N.S. | N.S. | |
| Small HDL | N.S. | N.S. | N.S. | |
N.S., non-significant; Interm., intermediate; *, p < 0.05 (conventional p-value); **, p < 0.005 (Bonferroni corrected p-value).