Table 2.

Logistic regression models evaluating the associations between clinical variables and hypertriglyceridemia and dyslipidemia in DLBCL patients.

Dependent variable	Independent variable	Univariable analysis		Multivariable analysis
		OR (95% CI)	P-value	OR (95% CI)	P-value
	Age	1.377 (0.816–2.321)	0.231	1.384 (0.715–2.677)	0.335
	Sex	0.989 (0.971–1.006)	0.199	0.879 (0.955–1.001)	0.062
	B symptoms	1.738 (0.989–3.053)	0.054	1.291 (0.627–2.661)	0.488
HTG	MCD subtype	3.150 (1.454–6.822)	0.004*	3.751 (0.721–19.507)	0.116
	BN2 subtype	2.362 (1.055–5.292)	0.037*	2.386 (0.907–6.272)	0.078
	EZB subtype	15.120 (4.387–47.260)	<0.001*	34.524 (3.700–322.120)	0.002*
	A53 subtype	2.520 (1.014–6.265)	0.047*	2.741 (0.977–7.692)	0.055
	BCL2 fusion mutation	4.104 (1.309-12.866)	0.015*	0.403 (0.034–4.814)	0.473
	ferritin	1.000 (1.000–1.001)	0.009*	1.000 (1.000–1.001)	0.167
	IL-10	1.001 (1.000–1.002)	0.096	1.001 (1.000–1.003)	0.135
	BMI	1.156 (1.058–1.265)	0.001*	1.183 (1.064–1.315)	0.002*
	Age	1.442 (0.877–2.371)	0.149	1.485 (0.805–2.739)	0.206
	Sex	0.990 (0.973–1.007)	0.238	0.976 (0.955–0.998)	0.035*
Dyslipidemia	B symptoms	2.178 (1.226–3.871)	0.008*	1.579 (0.764–3.264)	0.218
	MCD subtype	1.880 (0.938–3.768)	0.075	2.041 (0.405–10.287)	0.387
	BN2 subtype	1.642 (0.802–3.363)	0.175	1.261 (0.524–3.031)	0.605
	EZB subtype	10.108 (2.767–36.919)	<0.001*	14.931 (1.532–145.477)	0.020*
	A53 subtype	2.216 (0.958–5.126)	0.063	1.937 (0.732–5.123)	0.183
	BCL2 fusion mutation	7.232 (1.603–32.628)	0.010*	0.559 (0.041–7.714)	0.664
	ferritin	1.001 (1.000–1.002)	0.001*	1.001 (1.000–1.001)	0.026*
	IL-6	1.006 (1.000–1.009)	0.048*	1.002 (0.998–1.005)	0.306
	CRP	1.013 (1.011–1.019)	0.013*	1.000 (0.991–1.010)	0.979
	BMI	1.079 (0.992–1.172)	0.075	1.080 (0.975–1.195)	0.140

OR, odd ratio; CI, confidence interval; HTG, hypertriglyceridemia; IL-10, interleukin-10; BMI, Body Mass Index; IL-6, Interleukin-6; CRP, C-reactive protein.

*Significantly different.