Table 2.
Relationship between grading of lymph nodes status and clinicopathological features.
| Clinical characteristic | No. | Grade 1 | Grade 2 | Grade 3 | p valuea |
|---|---|---|---|---|---|
| Sex | 0.176 | ||||
| Male | 120 | 54 (45) | 46 (38.33) | 20 (16.67) | |
| Female | 48 | 17 (35.42) | 17 (35.42) | 14 (29.17) | |
| Age (years) | 0.595 | ||||
| ≤60 | 80 | 35 (43.75) | 27 (33.75) | 18 (22.5) | |
| >60 | 88 | 36 (40.91) | 36 (40.91) | 16 (18.18) | |
| Tumor long diameter (cm) | 0.001 | ||||
| ≤4.5 | 92 | 46 (50) | 37 (40.22) | 9 (9.78) | |
| >4.5 | 76 | 25 (32.89) | 26 (34.21) | 25 (32.89) | |
| Tumor differentiation | 0.002 | ||||
| Well-differentiated | 10 | 4 (40) | 6 (60) | 0 (0) | |
| Moderately differentiated | 48 | 26 (54.17) | 20 (41.67) | 2 (4.17) | |
| Poorly differentiated | 110 | 41 (37.27) | 37 (33.64) | 32 (29.09) | |
| Tumor location | 0.051 | ||||
| Upper third (U) | 25 | 11 (44) | 10 (40) | 4 (16) | |
| Middle third (M) | 39 | 16 (41.03) | 12 (30.77) | 11 (28.21) | |
| Lower third (L) | 94 | 39 (41.49) | 41 (43.62) | 14 (14.89) | |
| Others (U/M, M/L) | 10 | 5 (50) | 0 (0) | 5 (50) | |
| Surgical method | 0.091 | ||||
| Total gastrectomy | 45 | 16 (35.56) | 14 (31.11) | 15 (33.33) | |
| Proximal gastrectomy | 7 | 3 (42.86) | 4 (57.14) | 0 (0) | |
| Distal gastrectomy | 116 | 52 (44.83) | 45 (38.79) | 19 (16.38) | |
| Extent of lymph node dissection | 0.637 | ||||
| D0 | 151 | 65 (43.05) | 56 (37.09) | 30 (19.87) | |
| D1 | 5 | 2 (40) | 2 (40) | 1 (20) | |
| D1+ | 11 | 4 (36.36) | 5 (45.45) | 2 (18.18) | |
| D2 | 1 | 0 (0) | 0 (0) | 1 (100) | |
| TNM stage | <0.0001 | ||||
| I | 35 | 22 (62.86) | 13 (37.14) | 0 (0) | |
| II | 39 | 26 (66.67) | 13 (33.33) | 0 (0) | |
| III | 87 | 20 (22.99) | 36 (41.38) | 31 (35.63) | |
| IV | 7 | 3 (42.86) | 1 (14.29) | 3 (42.86) | |
| Depth of tumor invasion | <0.0001 | ||||
| T1 | 25 | 13 (52) | 12 (48) | 0 (0) | |
| T2 | 28 | 22 (78.57) | 6 (21.43) | 0 (0) | |
| T3 | 15 | 8 (53.33) | 2 (13.33) | 5 (33.33) | |
| T4 | 100 | 28 (28) | 43 (43) | 29 (29) | |
| Prognosis | <0.0001 | ||||
| Alive | 97 | 56 (57.73) | 35 (36.08) | 6 (6.19) | |
| Dead | 40 | 7 (17.5) | 18 (45) | 15 (37.5) | |
| Recurrence and distant metastasis | <0.0001 | ||||
| No | 101 | 53 (52.48) | 40 (39.6) | 8 (7.92) | |
| Yes | 67 | 18 (26.87) | 23 (34.33) | 26 (38.81) | |
| Lymph node metastasis | <0.0001 | ||||
| (-) | 54 | 30 (55.56) | 24 (44.44) | 0 (0) | |
| (+) | 114 | 41 (35.96) | 39 (34.21) | 34 (29.82) |
No., number of cases. a Bold values indicate significance, p<0.05.