Extended Data Fig. 7. Monotone reduction of cell proliferation due to controlled BACH1 expression increase.
Relative proliferation measurements at 0-, 24-, 48- and 72-hour time points for both low-noise and high-noise MB231-mNF-BACH1 clones (a), MB231-mNF-GFP clones (b), HEK293-mNF-BACH1 clones (d) and HEK293-mNF-GFP clones (e). (c) (f) Doubling times calculated for all selected clones of MB231 (c) and HEK293 (f). Doubling times were calculated using time points 0 and 48 h. One-way ANOVA, n = 3, *P < 0.05, **P < 0.01.