Duplicates removed	1
Excluded during initial screening (e.g. press releases; news reports; not relevant drug/indication; preclinical study; reviews; case reports; not randomized trial)	89
Excluded during writing (e.g. reviews; duplicate data; small patient number; nonrandomized/phase I/II trials)	71
Cited efficacy/tolerability articles	36
Cited articles not efficacy/tolerability	35
Search Strategy: EMBASE, MEDLINE and PubMed from 1946 to present. Clinical trial registries/databases and websites were also searched for relevant data. Key words were rimegepant, NURTEC, VYDURA, migraine, episodic migraine in adults. Records were limited to those in English language. Searches last updated 9 January 2023