Table 2.
Clinical laboratory parameters
| Parameter | N | Mean | SD | SEM | Median | Min | Max |
|---|---|---|---|---|---|---|---|
| Alanine aminotransferase (IU/L)a | |||||||
| Baseline | 14 | 17.1 | 5.8 | 1.56 | 16.0 | 9 | 26 |
| Day 3 | 14 | 21.9 | 19.3 | 5.15 | 15.0 | 9 | 83 |
| End of study | 14 | 17.2 | 8.0 | 2.13 | 15.0 | 8 | 35 |
| Aspartate aminotransferase (IU/L)b | |||||||
| Baseline | 14 | 16.6 | 3.3 | 0.89 | 16.0 | 13 | 25 |
| Day 3 | 14 | 17.8 | 9.1 | 2.44 | 15.0 | 12 | 48 |
| End of study | 14 | 16.9 | 2.9 | 0.78 | 16.5 | 11 | 22 |
| Total bilirubin (μmol/L)c | |||||||
| Baseline | 14 | 11.14 | 3.45 | 0.921 | 11.50 | 4.1 | 16.4 |
| Day 3 | 14 | 10.17 | 3.42 | 0.914 | 9.65 | 5.1 | 15.6 |
| End of study | 14 | 9.65 | 2.99 | 0.798 | 9.20 | 4.6 | 13.9 |
| Creatinine (µmol/L)d | |||||||
| Baseline | 14 | 63.0 | 15.7 | 4.21 | 59.5 | 43 | 97 |
| Day 3 | 14 | 61.1 | 14.5 | 3.87 | 54.5 | 43 | 92 |
| End of study | 14 | 61.8 | 13.8 | 3.69 | 58.0 | 43 | 90 |
IU, international unit; L, litre; Min, minimum; Max, maximum; N, number; SD, standard deviation; SEM, standard error mean
aNormal range 7–40 IU/L for female participants, 9–50 IU/L for male participants. bNormal range 13–35 IU/L for female participants, 15 to 40 IU/L for male participants. cNormal range 2.0–21.0 μmol/L. dNormal range 45–84 µmol/L for female participants, 59–104 µmol/L for male participants. Mean, SD, and median values are reported to 1 additional figure above the reported laboratory values; SEM values are reported to 2 additional significant figures