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. 2023 Jun 3;43(6):413–420. doi: 10.1007/s40261-023-01275-6
A single oral dose of 15 mg venglustat in healthy Chinese volunteers demonstrated a favorable pharmacokinetic profile that is compatible with once daily oral dosing with no relevant differences between male and female participants.
Pharmacokinetic parameters (Cmax and AUCinf) in healthy Chinese volunteers were generally comparable to those in non-Chinese volunteers in a post hoc cross-study comparison.
Venglustat was safe and well tolerated in all Chinese volunteers, and there were no specific safety concerns identified.