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. 2023 Jun 13;21:3383–3403. doi: 10.1016/j.csbj.2023.06.011

Fig. 2.

Fig. 2

Transcriptional alterations, genetic characteristics and clinical values of CPRMs in CRC. A. The thermogram shows the different mRNA expression levels of 16 CPRMs between the normal and tumor samples in pan-cancer from TCGA cohorts. T-test: * P < 0.05, * * P < 0.01, * ** P < 0.001. B. The waterfall diagram shows the somatic mutation frequency of 16 CPRMs in pan-cancer. C. The bubble chart shows the correlation between CNV and mRNA expression levels of 16 CPRMs in pan-cancer using Spearman correlation analysis. D. The bubble chart shows the relationship between prognosis and mRNA expression levels of 16 CPRMs in pan-cancer using the Log-rank test. E. The boxplot shows the different cuproptosis ssGSEA scores between the normal and tumor samples in pan-cancer. T-test: * P < 0.05, * * P < 0.01, * ** P < 0.001. F. The thermogram shows the correlation between mRNA expression levels of 16 CPRMs and 28 TME infiltrating cells or 50 common molecular biology pathways in pan-cancer. Spearman correlation analysis: * P < 0.05, * * P < 0.01, * ** P < 0.001.