Fig. 6.

Single-cell transcriptome analysis of CRC cells based on cuproptosis-related molecular classification. A. The volcano map shows the different single-cell mRNA expression levels of 16 CPRMs between 1070 normal and 17,469 tumor epithelial cells. B. The t-SNE visualization shows the different single-cell distributions between the two cuproptosis phenotypes. C. The t-SNE visualizations show the molecular expression of 16 CPRMs except MTF1. D. The stacked histogram shows variations in the proportion and number of molecular and clinical characteristics between the two cuproptosis single-cell phenotypes. E-F. The bar plots show the results of GO (E) and KEGG (F) analysis of the differentially expressed genes between the two cuproptosis single-cell phenotypes.