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. 2023 Jun 13;21:3383–3403. doi: 10.1016/j.csbj.2023.06.011

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© 2023 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 8 — Predictive value of CuproScore for immunotherapy response. A. The violin plots show variations in CuproScore between groups with high or low immunotherapy sensitivity scores in the TCGA-COREAD cohorts. B. The Kaplan-Meier curve shows the significant difference in the survival rate between the high and low CuproScore groups in the IMvigor210 cohort using the best cut-off value. C. The violin plot shows variation in CuproScore between groups with different anti-PD-L1 responsiveness. D. The stacked histogram shows variations in the proportion of different anti-PD-L1 responsiveness between the high and low CuproScore groups. E. The violin plot shows variations in CuproScore among three immune phenotypes. F-G. The violin plots show variations in CuproScore among PD-L1 expression of different IC (F) and TC (G). H-I. The Kaplan-Meier curve (H) and stacked histogram (I) show the potential predictive value of CuproScore for anti-PD-L1 immunotherapy in Liu’s dataset.