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. 2023 Jun 13;21:3383–3403. doi: 10.1016/j.csbj.2023.06.011

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© 2023 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 11 — The effects of cuproptosis inducer Elesclomol-Cu²⁺ on 16 CPRMs in CRC cell lines. A-D. The boxplots show the different mRNA expression levels of 16 CPRMs in HT29 (A), HCT116(B), SW620 (C) and SW480 (D) cell lines after being treated with Elesclomol-Cu²⁺ and D-penicillamine using real-time PCR. E-F. The western blots and boxplots show the four protein expression levels of hub CPRMs (DLAT, LIAS, FDX1 and SLC31A1) in HT29 (E) and SW620 (F) cell lines after being treated with Elesclomol-Cu²⁺ and D-penicillamine using Western Blot. One-way ANOVA: ^nsP > 0.05, * P < 0.05, * * P < 0.01, * ** P < 0.001.