Table 2.
Unadjusted and adjusted breast cancer mortality hazard ratios
Unadjusted Hazard Ratios | p-value | Adjusted Hazard Ratios* | p-value | |
---|---|---|---|---|
Age at diagnosis | ||||
< 50 years | 1 (Ref) | 1 (Ref) | ||
≥ 50 years | 0.71 (0.52–0.95) | 0.024 | 0.97 (0.71–1.32) | 0.829 |
Linear Trend | 0.99 (0.98–1.00) | 0.131 | 1.01 (0.99–1.02) | 0.483 |
Molecular Subtype | ||||
Luminal A | 1 (Ref) | 1 (Ref) | ||
Luminal B | 1.24 (0.78–1.98) | 0.365 | 1.09 (0.68–1.75) | 0.716 |
HER2-enriched | 2.38 (1.49–3.80) | < 0.001 | 1.85 (1.15–2.98) | 0.011 |
;Basal like | 2.07 (1.29–3.33) | 0.003 | 1.93 (1.20–3.10) | 0.007 |
HIV status | ||||
;HIV negative | 1 (Ref) | 1 (Ref) | ||
;HIV positive | 2.08 (1.55–2.80) | < 0.001 | 2.14 (1.58–2.90) | < 0.001 |
Stage at diagnosis | ||||
Early stage (1 and 2) | 1 (Ref) | 1 (Ref) | ||
Advanced stage (3 and 4) | 3.59 (2.56–5.02) | < 0.001 | 3.65 (2.60–5.12) | < 0.001 |
Risk of recurrence | ||||
Low | 1 (Ref) | 1 (Ref) | ||
Intermediate | 0.78 (0.30–2.03) | 0.615 | 1.00 (0.38–2.62) | 0.993 |
High | 2.66 (1.36–5.19) | 0.004 | 2.18 (1.11–4.28) | 0.023 |
Linear Trend | 1.01 (1.01–1.02) | 0.002 | 1.01 (1.00–1.02) | 0.049 |
*Adjusted for age, stage, HIV status