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. 2023 Jun 2;200(3):337–346. doi: 10.1007/s10549-023-06969-1

Table 2.

Unadjusted and adjusted breast cancer mortality hazard ratios

Unadjusted Hazard Ratios p-value Adjusted Hazard Ratios* p-value
Age at diagnosis
  < 50 years 1 (Ref) 1 (Ref)
  ≥ 50 years 0.71 (0.52–0.95) 0.024 0.97 (0.71–1.32) 0.829
 Linear Trend 0.99 (0.98–1.00) 0.131 1.01 (0.99–1.02) 0.483
Molecular Subtype
 Luminal A 1 (Ref) 1 (Ref)
 Luminal B 1.24 (0.78–1.98) 0.365 1.09 (0.68–1.75) 0.716
 HER2-enriched 2.38 (1.49–3.80)  < 0.001 1.85 (1.15–2.98) 0.011
 ;Basal like 2.07 (1.29–3.33) 0.003 1.93 (1.20–3.10) 0.007
HIV status
 ;HIV negative 1 (Ref) 1 (Ref)
 ;HIV positive 2.08 (1.55–2.80)  < 0.001 2.14 (1.58–2.90)  < 0.001
Stage at diagnosis
 Early stage (1 and 2) 1 (Ref) 1 (Ref)
 Advanced stage (3 and 4) 3.59 (2.56–5.02)  < 0.001 3.65 (2.60–5.12)  < 0.001
Risk of recurrence
 Low 1 (Ref) 1 (Ref)
 Intermediate 0.78 (0.30–2.03) 0.615 1.00 (0.38–2.62) 0.993
 High 2.66 (1.36–5.19) 0.004 2.18 (1.11–4.28) 0.023
 Linear Trend 1.01 (1.01–1.02) 0.002 1.01 (1.00–1.02) 0.049

*Adjusted for age, stage, HIV status