Table 3.

Unadjusted and adjusted hazard ratios for disease recurrence

Hazard Ratios for Disease Free Survival
	Unadjusted	p-value		Adjusted for age, stage, hiv	p-value
	Hazard Ratio			Hazard Ratio
Age at diagnosis
< 50 years	1 (Ref)			1 (Ref)
≥ 50 years	0.63 (0.45–0.88)	0,007		0.86 (0.60–1.22)	0,397
Linear Trend	0.99 (0.97–1.00)	0,134		1.00 (0.98–1.02)	0,904
Molecular Subtype
Luminal A	1 (Ref)			1 (Ref)
Luminal B	1.24 (0.73–2.09)	0,429		1.19 (0.70–2.02)	0,521
Her2-enriched	2.03 (1.20–3.45)	0,009		1.56 (0.91–2.68)	0,104
;Basal like	2.37 (1.41–3.98)	0,001		2.29 (1.37–3.85)	0,002
HIV status
;HIV negative	1 (Ref)			1 (Ref)
;HIV positive	2.30 (1.65–3.19)	< 0.001		2.26 (1.62–3.16)	< 0.001
Stage at diagnosis
Early stage (1 and 2)	1 (Ref)			1 (Ref)
Advanced stage (3 and 4)	2.82 (2.00–3.97)	< 0.001		2.77 (1.96–3.90)	< 0.001
Risk of recurrence
Low	1 (Ref)		1 (Ref)
Intermediate	0.84 (0.29–2.40)	0,739	1.11 (0.39–3.20)			0,844
High	2.88 (1.35–6.15)	0,006	2.48 (1.15–5.31)			0,02
Linear Trend	1.01 (1.00–1.02)	0,014	1.01 (1.66–3.24)			< 0.001
Viral Load
Undetectable	1 (Ref)		1 (Ref)
Detectable	0.86 (0.54–1.35)	0,503	0.73 (0.46–1.16)			0,178
ART status
No	1 (Ref)		1 (Ref)
Yes	0.83 (0.51–1.37)	0,466	0.89 (0.53–1.49)			0,657
Duration of ART
≤ 1 year	1 (Ref)		1 (Ref)
> 1 year	0.68 (0.36–1.29)	0,236	0.68 (0.36–1.29)			0,236
CD4 count
< 200	1 (Ref)		1 (Ref)
≥ 200	0.53 (0.30–0.95)	0,032	0.60 (0.33–1.07)			0,082

*Adjusted for age, stage, HIV status