Skip to main content
. 2023 Jun 15;9(6):e17326. doi: 10.1016/j.heliyon.2023.e17326

Table 1.

Effect of gallic acid (GA) oral dosing on body weight change and hepatosomatic index of Sprague Dawley rats exposed to zinc dioxide nanoparticles (ZNPs) and/or arsenic trioxide (ATO) for 60 days.

Estimated parameters Control GA ZNPs % of control* ATO % of control* ZNPs+ATO % of control* GA+ZNPs+ATO % of restoration
Initial Body weight (g) 213.33 ± 4.71 206.67 ± 4.71 206.67 ± 4.71 97 206.67 ± 4.71 97 200.00 ± 0.00 94 206.67 ± 4.71 103
Final body weight (g) 266.00a ±5.72 272.67a±2.62 223.67c±0.24 84 215.00cd ± 7.18 81 207.33 d ± 0.62 78 238.33 b ± 3.06 115
Body weight gain (g) 52.67 b ± 5.91 66.00a±6.16 17.00 d ± 4.60 32 8.33 d ± 2.66 16 7.33 d ± 0.62 14 31.67c±1.65 432
Liver weight (g) 6.46 ± 0.27 6.98 ± 0.14 6.13 ± 0.43 95 6.35 ± 0.41 98 6.45 ± 0.10 100 6.00 ± 0.32 93
Hepatosomatic index (%) 2.43c ±0.12 2.56 bc±0.03 2.74 abc±0.19 113 2.96 ab ± 0.19 122 3.11a±0.06 128 2.52c±0.13 81

*% of control = (mean value of the intoxicated group/mean values of the control group)*100. % of restoration= (mean value of GA+ZNPs+ATO group/mean values of ZNPs+ATO group)*100. Means within the same row carrying different superscripts (a, b, c, and d) are significantly different at p < 0.05. The values shown are means ± SE. n = 10.