TABLE 5.
Modified from Bronaugh et al. (Bronaugh and Stewart, 1985) Comparison of flow-through and static-diffusion cell absorption. Values are listed as the mean ± standard error of the mean of the number of determinations in parentheses. Cortisone and benzoic acid were given with an acetone vehicle. Their absorption is displayed as the percent of the dose absorbed in 24 h. Water was given with a water vehicle and the steady state rate of absorption is expressed in μg/cm2⋅h.
| Compound | Flow cell | Static cell |
|---|---|---|
| Water | 4.3 ± 0.4 (5) | 4.4 ± 0.2 (5) |
| Cortisone | 8.5 ± 0.9 (5) | 6.3 ± 0.8 (8) |
| Benzoic Acid | 45.9 ± 7.6 (5) | 48.6 ± 3.8 (6) |