Fig. 4.

Fluorescence intensity of coronal brain slices of rats indicating the appearance of the low molecular weight tracer OA-45 (45 kDa) at the level of bregma + 1.5 mm ∼ − 3.5 mm. All procedures were as described in the Legend to Fig. 1, except the duration of TST, which was increased from 5 to 15 min. Means±S.E.M. from 6 animals. *P < 0.05; statistically significant difference from the control value. ^#P < 0.05; statistically significant difference from the respective TST values. One-way ANOVA followed by the Holm-Sidak (A, C) or Tukey test (B) were used as adequate. Two brain slices are shown out of the 6 slices prepared from each brain for the indicated treatments (D).