Figure 2.

Quercetin, cyanidin, and their O-glucosides’ channel-like activity in DOPS:DOPE:POPC PLMs. Example of chart recordings of channel-like activity of quercetin (A), quercetin-4′-O-glucoside (B), cyanidin (C), and cyanidin-3-O-glucoside (D) in PLMs made up of DOPS:DOPE:POPC with associated histograms of the conductance fluctuations. The histograms of the probability, P(Λ), for the frequency of a given conductivity unit were fitted by a Gaussian distribution, which is shown as a solid curve. Experiments were performed in the presence of the different compounds (0.02 mg/mL) added to the cis side, while the aqueous phase contained 1 M KCl (pH 7) and T = 23 ± 1 °C. Applied voltage was set to 40 mV.