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Schematic model of the four flavonoids’ interaction with DOPS:DOPE:POPC PLM. Quercetin-4′-O-glucoside and cyanidin-3-O-glucoside adsorb onto the membrane surface (top), while quercetin and cyanidin localize at the interface between the polar region of head groups and the hydrophobic core of the bilayer (bottom). The incorporation of the four flavonoids into the membrane and the formation of conductive units influences the electrical properties of PLM.
