Table 3.

List of target miRNAs with a focus on their associations with breast cancer and bacterial infection.

miRNA	General Overview	Role in Breast Cancer/Infections
miR-206	Oncogene	Upregulated expression of this miRNA has been found in breast cancer [28]. Associated with MMP9 and acts in the hemorrhagic transformation of cardioembolic stroke [32]; and also plays a role in TIMP3 induction, with mycobacterial infection observed [33]. Observed upregulated expression with mycobacterial infection [34].
miR-214-3p	Oncogene	Upregulated expression associated with the progression of triple-negative breast cancer [29]. Affects the PI3K/Akt/mTOR pathway and promotes breast cancer development [29]. Differentially expressed in B. burgdorferi-infected primary human astrocytes [35].
miR-16-5p	Tumor suppressor	The upregulated expression leads to the inhibition of the progress of the cell cycle and the proliferation of breast cancer cells [30]. Dysregulated expression has been found in H. Pylori-infected gastric epithelial cells [36].
miR-20b-5p	Oncogene	Upregulated expression results in increased migration and proliferation of breast cancer cells [31]. Promotes tumor development and influences PTEN gene expression in breast cancer [37].