Table 1.
Operational taxonomic unit (OTU)-based diversity index in rat oral cavity and fecal samples in the mTBI model.
| Sample Name | Sample Group | Sample Region | Sample Time | Clean Tags | Valid Tags | OTUs | Chao1 Index | Shannon Index | Observed Species |
|---|---|---|---|---|---|---|---|---|---|
| MC1.1 | Group MC1 | oral | Sham (0 h) | 75,337 | 67,337 | 1798 | 3116.86 | 4.52 | 1682 |
| MC1.2 | 76,332 | 68,857 | 1742 | 2886.53 | 5.28 | 1612 | |||
| MC1.3 | 75,656 | 69,597 | 1712 | 2802.71 | 6.17 | 1582 | |||
| ME1.1 | Group ME1 | oral | 0 h post-injury | 71,304 | 66,447 | 546 | 819.09 | 7.23 | 528 |
| ME1.2 | 77,807 | 73,239 | 1869 | 2866.49 | 5.47 | 1691 | |||
| ME1.3 | 77,425 | 67,121 | 1760 | 2474.31 | 6.58 | 1685 | |||
| ME2.1 | Group ME2 | oral | 2 h post-injury | 72,793 | 68,057 | 535 | 884.99 | 7.22 | 514 |
| ME2.2 | 76,474 | 72,318 | 1166 | 2270.56 | 5.70 | 1042 | |||
| ME2.3 | 75,877 | 71,371 | 1289 | 1987.34 | 6.28 | 1185 | |||
| ME3.1 | Group ME3 | oral | 6 h post-injury | 76,912 | 72,968 | 971 | 2066.67 | 4.54 | 856 |
| ME3.2 | 76,203 | 71,150 | 1081 | 1998.34 | 4.95 | 975 | |||
| ME3.3 | 77,008 | 72,957 | 969 | 1830.47 | 4.02 | 863 | |||
| ME4.1 | Group ME4 | oral | 12 h post-injury | 77,558 | 73,279 | 1174 | 1972.13 | 5.56 | 1047 |
| ME4.2 | 74,410 | 69,148 | 1468 | 2464.91 | 6.77 | 1353 | |||
| ME4.3 | 74,541 | 61,390 | 2806 | 3991.49 | 8.79 | 2762 | |||
| ME5.1 | Group ME5 | oral | 24 h post-injury | 75,928 | 71,806 | 985 | 1931.79 | 4.61 | 885 |
| ME5.2 | 74,611 | 69,202 | 1394 | 2224.90 | 6.53 | 1300 | |||
| ME5.3 | 74,028 | 67,273 | 1459 | 2480.35 | 6.51 | 1376 | |||
| ME6.1 | Group ME6 | oral | 2 d post-injury | 74,664 | 68,074 | 1229 | 2111.26 | 6.60 | 1142 |
| ME6.2 | 75,143 | 70,151 | 1405 | 2415.12 | 6.57 | 1287 | |||
| ME6.3 | 75,263 | 70,114 | 1465 | 2383.18 | 5.98 | 1353 | |||
| ME7.1 | Group ME7 | oral | 3 d post-injury | 76,769 | 72,196 | 1344 | 2391.90 | 6.05 | 1220 |
| ME7.2 | 76,083 | 66,074 | 2417 | 3860.69 | 6.20 | 2298 | |||
| ME7.3 | 75,138 | 70,342 | 1340 | 2233.28 | 6.07 | 1235 | |||
| ME8.1 | Group ME8 | oral | 5 d post-injury | 73,677 | 64,813 | 1646 | 2536.52 | 7.65 | 1586 |
| ME8.2 | 73,510 | 67,294 | 1480 | 2269.39 | 6.76 | 1399 | |||
| ME8.3 | 75,149 | 69,671 | 1307 | 2133.34 | 6.04 | 1211 | |||
| ME9.1 | Group ME9 | oral | 7 d post-injury | 76,487 | 71,464 | 1041 | 1980.39 | 5.41 | 934 |
| ME9.2 | 77,256 | 73,332 | 1412 | 2236.65 | 6.37 | 1280 | |||
| ME9.3 | 76,074 | 72,053 | 1250 | 2131.06 | 5.38 | 1131 | |||
| ME10.1 | Group ME10 | oral | 10 d post-injury | 74,698 | 64,240 | 2438 | 3771.06 | 7.41 | 2351 |
| ME10.2 | 75,988 | 71,686 | 1417 | 2241.45 | 6.21 | 1230 | |||
| ME10.3 | 77,097 | 72,449 | 1119 | 1926.33 | 4.38 | 1012 | |||
| ME11.1 | Group ME11 | oral | 14 d post-injury | 73,656 | 68,661 | 1048 | 2039.08 | 4.96 | 958 |
| ME11.2 | 77,171 | 71,986 | 1224 | 1992.04 | 5.56 | 1115 | |||
| ME11.3 | 74,442 | 69,983 | 1351 | 2350.88 | 6.09 | 1243 | |||
| FC1.1 | Group FC1 | fecal | Sham (0 h) | 74,549 | 63,224 | 4644 | 6350.08 | 8.17 | 4526 |
| FC1.2 | 78,141 | 69,901 | 4212 | 5464.17 | 8.02 | 3962 | |||
| FC13 | 78,353 | 71,439 | 3795 | 4908.06 | 7.73 | 3545 | |||
| FE1.1 | Group FE1 | fecal | 0 h post-injury | 72,912 | 62,697 | 4252 | 5677.05 | 8.04 | 4163 |
| FE1.2 | 78,371 | 73,562 | 4248 | 5714.62 | 7.13 | 3893 | |||
| FE1.3 | 75,060 | 67,562 | 3683 | 4874.46 | 7.75 | 3510 | |||
| FE2.1 | Group FE2 | fecal | 2 h post-injury | 71,387 | 59,683 | 4025 | 5746.62 | 7.67 | 4009 |
| FE2.2 | 76,979 | 71,123 | 3315 | 4509.30 | 7.16 | 3087 | |||
| FE2.3 | 71,929 | 66,019 | 4046 | 5535.51 | 7.97 | 3873 | |||
| FE3.1 | Group FE3 | fecal | 6 h post-injury | 76,357 | 69,373 | 4201 | 5769.69 | 7.50 | 3937 |
| FE3.2 | 71,151 | 64,398 | 4662 | 6083.80 | 8.61 | 4527 | |||
| FE3.3 | 76,482 | 71,302 | 4322 | 5782.13 | 7.58 | 4025 | |||
| FE4.1 | Group FE4 | fecal | 12 h post-injury | 77,589 | 70,057 | 4805 | 6143.82 | 8.29 | 4525 |
| FE4.2 | 75,067 | 68,011 | 5191 | 6714.32 | 8.97 | 4932 | |||
| FE4.3 | 74,220 | 64,371 | 5193 | 7173.78 | 8.75 | 5021 | |||
| FE5.1 | Group FE5 | fecal | 24 h post-injury | 75,389 | 69,399 | 4327 | 5750.95 | 7.55 | 4070 |
| FE5.2 | 78,288 | 70,851 | 5166 | 6721.96 | 8.91 | 4832 | |||
| FE5.3 | 76,998 | 72,103 | 4023 | 5302.52 | 6.92 | 3733 | |||
| FE6.1 | Group FE6 | fecal | 2 d post-injury | 75,178 | 68,839 | 3498 | 4916.26 | 6.86 | 3285 |
| FE6.2 | 75,699 | 68,243 | 4924 | 6399.17 | 8.72 | 4667 | |||
| FE6.3 | 74,516 | 70,555 | 3178 | 4486.95 | 5.69 | 2948 | |||
| FE7.1 | Group FE7 | fecal | 3 d post-injury | 78,591 | 72,364 | 3501 | 4790.55 | 6.66 | 3216 |
| FE7.2 | 77,339 | 66,454 | 5600 | 7714.87 | 9.16 | 5342 | |||
| FE7.3 | 76,786 | 71,029 | 3803 | 5228.15 | 6.62 | 3527 | |||
| FE8.1 | Group FE8 | fecal | 5 d post-injury | 76,586 | 69,471 | 4473 | 5927.13 | 8.25 | 4206 |
| FE8.2 | 77,399 | 70,549 | 4892 | 6248.60 | 8.84 | 4602 | |||
| FE8.3 | 75,925 | 69,016 | 4343 | 5654.33 | 7.81 | 4094 | |||
| FE9.1 | Group FE9 | fecal | 7 d post-injury | 77,773 | 69,274 | 4429 | 5948.41 | 8.49 | 4175 |
| FE9.2 | 75,311 | 66,071 | 4749 | 6271.71 | 9.00 | 4559 | |||
| FE9.3 | 75,555 | 67,513 | 4811 | 6270.56 | 8.99 | 4586 | |||
| FE10.1 | Group FE10 | fecal | 10 d post-injury | 73,875 | 63,280 | 5193 | 7001.54 | 9.00 | 5059 |
| FE10.2 | 78,491 | 68,669 | 4813 | 6325.99 | 8.88 | 4550 | |||
| FE10.3 | 78,304 | 70,052 | 4902 | 6306.22 | 8.83 | 4607 | |||
| FE11.1 | Group FE11 | fecal | 14 d post-injury | 77,742 | 68,515 | 4508 | 5955.91 | 8.09 | 4252 |
| FE11.2 | 75,851 | 68,780 | 4427 | 5705.18 | 8.23 | 4183 | |||
| FE11.3 | 77,711 | 67,696 | 5252 | 6594.63 | 9.21 | 5017 |