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. 2023 Jun 20;59(6):1177. doi: 10.3390/medicina59061177

Table 1.

Characteristics of studies included in our meta-analysis.

BMD Group
Author, year Country Study design Study population (age in years) Groups Number of participants Bone mineral density mean difference
Coffee
Ye, 2021 [34] China Cross-sectional Postmenopausal women (47–90) ≥2 cups/day vs. 0 cups/day 648 0.16
Hallström, 2010 [35] Sweden Prospective cohort Men and women (72) >4 cups/day vs. 0–2 cups/day 717 0.02
Lloyd, 1997 [36] United States Cross-sectional Postmenopausal White women (55–70) ≥5 cups/day vs. 0–2 cups/day 138 0.02
Tea
Ni, 2021 [37] China Cross-sectional Postmenopausal women (<80) Drinkers vs.
nondrinkers
1377 0.151
Li, 2021 [38] China Cross-sectional Postmenopausal women Daily drinkers vs. nondrinkers 947 0.027
Huang, 2018 [39] China Prospective cohort Women (≥40) ≥7 times/week vs. ≤1 time/week 1495 0.016
Wang, 2014 [40] China Cross-sectional Postmenopausal women (62.2519 ± 6.2837) ≥1 cup/day vs. 0 cup/day 680 0.031
Devine, 2007 [41] Australia Cross-sectional Postmenopausal women (70–85) ≥5 cups/day vs. 0 cup/day 1027 0.015
Chen, 2003 [11] United States Prospective cohort Postmenopausal women (50–79) ≥5 cups/day vs. <1 cup/day 91,465 0.000
Hegarty, 2000 [42] United Kingdom Cross-sectional Postmenopausal women (65–76) >6 cups/day vs.
0 cup/day
1256 0.048
Hip Fracture Group
Author, year Country Design Study population (age in years) Groups Number of participants Number of hip fracture cases Hazard ratio (95% confidence interval)
Coffee
Dai, 2018 [25] Singapore Prospective cohort Men and women (45–74) ≥4 cups/day vs. <1 cup/week 63,154 2502 1.32 (1.07–1.63)
Hallström, 2014 [23] Sweden Prospective cohort Men (45–79) ≥4 cups/day vs. <1 cup/day 42,978 1186 0.89 (0.70–1.14)
Hallström, 2013 [17] Sweden Prospective cohort Women (not available) ≥4 cups/day vs. <1 cup/day 61,433 3871 0.88 (0.78–1.00)
van-Lenthe, 2011 [21] The Netherlands Prospective cohort Women (25–74) ≥3 cups/day vs. 0 cup/day 16,578 192 0.75 (0.42–1.36)
Trimpou, 2010 [19] Sweden Prospective cohort Men (46–56) ≥5 cups/day vs. 0 cup/day 7495 451 0.55 (0.42–0.73)
Meyer, 1997 [14] Norway Prospective cohort Men and women (35–49) ≥9 cups/day vs. <1 cup/day 39,787 213 Women: 1.94 (0.96–3.91)
Men: 1.04 (0.37–2.94)
Hernandez-Avila, 1991 [28] United States Prospective cohort Women (34–59) ≥4 cups/day vs. individuals who rarely drank coffee 84,484 65 3.35 (1.32–8.49)
Tea
Dai, 2018 [25] Singapore Prospective cohort Men and women (45–74) Daily vs.
less frequent than weekly
63,154 2502 0.95 (0.85–1.06)
Myers, 2015 [24] Australia Prospective cohort Postmenopausal women (>75) ≥3 cups/day vs. ≤1 cup/day 1188 129 0.65 (0.40–1.06)
Chen, 2003 [11] United States Prospective cohort Postmenopausal women (50–79) ≥5 cups/day vs. <1 cup/day 91,465 386 0.93 (0.44–1.98)
Hernandez-Avila, 1991 [26] United States Prospective cohort Women (34–59) ≥2 cups/day vs. individuals who rarely drank tea 84,484 65 0.71 (0.29–1.73)