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. 2023 May 16;3(6):1539–1553. doi: 10.1021/jacsau.3c00014

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(a,b) Seminal examples of bicyclo[1.1.1]pentanes (BCPs) as para-substituted arene bioisosteres.^3,4 (c) Dimensions of the BCP and other cage hydrocarbons as linear bioisosteres.