| Are the hypothesis and objective of the study clearly described? |
| Are the main outcomes to be measured clearly described? |
| Are the main findings of the study clearly described? |
| Are the samples size calculations reported? |
| Are the animals randomly housed during the experiment? |
| Are the investigators blinded from knowledge which treatment used? |
| Are the outcome assessors blinded? |
| Is the dose/route of administration of Citrus medica L. properly reported? |
| Is the dose/route of administration of the drug in co-treatment properly reported? |
| Is the frequency of treatments adequately described? |
