Sleeve gastrectomy (SG)
|
Mechanical and hormonal weight loss. No interference with corticosteroid pharmacokinetics. Easier access in the event of gastric variceal bleeding. Maintains access to the biliary system. |
Development of Gastroesophageal Reflux Disease (GERD). |
Mittal et al., 2021 [220] |
Laparoscopic adjustable gastric banding (LAGB)
|
Lower early complications and shorter operative time and length of stay. |
Interference with corticosteroid pharmacokinetics. Not the most effective surgical procedure to reducing weight. |
Tichansky et al., 2005 [221] |
Roux-en-Y gastric bypass (RYGB)
|
Reduction of reflux gastritis and esophagitis. It improved glycemic control and high-density lipoprotein levels. |
No access to the biliary system. Possible development of a stomal ulcer. Increased probability of cholelithiasis and Roux stasis syndrome. Interference with corticosteroid pharmacokinetics. |
Tichansky et al., 2005 [221] |
Intragastric balloon (IGB)
|
Non-invasive and rapid procedure. Rapid weight loss. |
Upper gastrointestinal bleeding. Increase in liver fat fraction. Rapid weight loss. Not durable. |
Watt et al., 2021 [223] |
Timing |
Pro |
Cons |
Reference |
Before LT |
Resolution of obesity-related comorbidities. |
Increased costs. Two different hospitalisations. Increased patient discomfort and delayed LT. Worsening sarcopenia and malnourishment of the patient. |
Diwan et al., 2018 [225] |
During LT |
Resolution of obesity-related comorbidities. Costs and patient discomfort are minimised. |
The complexity of the procedure. |
Tariciotti et al., 2016 [228] |
After LT |
Decrease in obesity-related comorbidities after LT. |
Increased susceptibility to infections. Poor wound healing. Hostile abdominal environment after LT. |
Lin et al., 2013 [232] |