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. 2023 Jun 16;15(6):1750. doi: 10.3390/pharmaceutics15061750

Figure 1.

Figure 1

Parameters and strategies for designing scaffolds for brain tissue engineering. In the blue circle, the main parameters to be considered in the design of scaffolds are addressed. The main strategies to cover each parameter are described in the yellow circle. In the green circle, some examples are presented. BNDF: brain-derived neurotrophic factor; VEGF: vascular endothelial growth factor; TFG-β: transforming growth factor-beta; ROS: reactive oxygen species; RGD: arginine-glycine-aspartate.