. Author manuscript; available in PMC: 2023 Dec 1.

Published in final edited form as: Adv Drug Deliv Rev. 2022 Oct 19;191:114581. doi: 10.1016/j.addr.2022.114581

Table 2.

Excipients (polymers and additives) that may be potentially used in the formulation of LNG-IUSs.

Component	Formulation variables
Polymers	Polydimethylsiloxane-based (PDMS) (silicones)
	Different attributes- molecular weight, viscosities, chain length, etc.
	Functional group substitutions
	Dimethyl-substituted
	Phenyl-substituted
	Fluoro-substituted
	Ethyl-substituted
	End-groups
	Alkyl (methyl, ethyl, or propyl)
	Aminopropyl
	Hydroxyl
Additives	Silica
	Diatomaceous earth
	Silicone resins
	Silicone oil