Figure 4.

Heatmap showing the distribution of putative antimicrobial resistance and heavy-metal-resistance genes in each A. butzleri genome. Gene names or their locus tags are shown for each gene considered. ^An alternative transcriptional regulator (annotated as SlyA) of the RND (resistance-nodulation-division) system BepDE (EP4) was detected in eight strains isolated from environmental water (W20, W23, W44, W46, W50) and chicken meat (CH11, CH37, CH58). Numbers 1 to 7 (Pearson’s correlation-based hierarchical tree) indicate the seven groups that were observed in the cgSNP phylogeny and in the accessory genome-based hierarchic tree (Figure 2 and Figure 3, respectively). EP—efflux pump, T1SS—type I secretion system.