Figure 6.

Representative images from tissues of heads of Balb/c mice infected with VEEV TrD subcutaneously and stained for viral RNA using in situ hybridisation. Despite an absence of overt histopathological changes, low levels of viral RNA were detected in the nasal cavity (A) and the mandibular lymph nodes (B) at 3+ days post-infection, with a clinical score of 2. A section across the cribriform plate (C) reveals an absence of viral RNA in the nerves from the nasal cavity to the olfactory bulb, but it was present within blood vessels of the olfactory bulb at 5 days post-infection (clinical score of 7).