Table 1.

Quantitative score assigned to tissue sections from the brains and nasal compartments of Balb/c mice infected with VEEV TrD.

Pathology Score	Histopathological Lesions in the Brain	Perivascular Cuffing within Meninges	Histopathology in the Nasal Cavity (inc. Mucosa)
0	Within normal limits	Within normal limits	Within normal limits
1	Minimal spongiosis	Minimal	Minimal
2	Mild spongiosis and minimal to mild increase in neuropil cellularity (glia)	Mild	Mild
3	Moderate spongiosis and mild neuronal death (as observed within neuronal soma) Moderate increase in neuropil cellularity (glia)	Moderate	Moderate
4	Moderate to severe spongiosis and neuronal death (as observed within neuronal soma) Moderate increase in neuropil cellularity (glia)	Marked/severe	Marked/severe necrosis of mucosa and presence of exudate within lumen