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Technology roadmap of study. 32 ICD-associated genes were collected from previous studies and used to construct a prognosis model in the TCGA cohort and the GEO cohort; 14 IRGs-related TDGs were used to construct AI models based on IRGs-based clustering; 14 IRGs-TDGs-based and genome-based drug sensitivity prediction; The role of PTPRC in regulating CD8+ T cells infiltration-mediated chemotherapy sensitized.
