Table 1.
Comparison of missense and synonymous mutation frequency profiles of SARS-CoV-2 omicron sublineage BA.1 in Thailand datasets (nt length 29,544 bp).
| Lineage | Gene | nt Position | aa Position | Genome Count | Frequency |
|---|---|---|---|---|---|
| BA.1 | ORF1ab | T2019C | M585T | 135 | 16.40 |
| (n = 823) | C2470T | 89 | 10.81 | ||
| G5515T | 5 | 0.61 | |||
| G6850T | 146 | 17.74 | |||
| C15952T | 3 | 0.36 | |||
| S | G23628A | S689N | 99 | 12.03 | |
| C26936T | 58 | 7.05 | |||
| BA.1.1 | ORF1ab | C2470T | 1374 | 96.83 | |
| (n = 1419) | G3692A | V1143I | 8 | 0.56 | |
| G3896T | V1211F | 21 | 1.48 | ||
| G6109A | 75 | 5.29 | |||
| C11750T | L3829F | 11 | 0.78 | ||
| G12661A | 116 | 8.17 | |||
| C14805T | 735 | 51.80 | |||
| G18433A | D1656N | 35 | 2.47 | ||
| T19632C | 744 | 52.43 | |||
| ORF3a | G25634A | C81Y | 8 | 0.56 | |
| E | G26428T | V62F | 12 | 0.85 | |
| M | A26530G | D3G | 1060 | 74.70 | |
| N | C28838T | R189C | 29 | 2.04 | |
| BA.1.1.5 | ORF1ab | C14117T | T217M | 51 | 64.56 |
| (n = 79) | S | C21597T | S12F | 6 | 7.59 |
| M | A26530G | D3G | 65 | 82.28 | |
| BA.1.1.8 | ORF1ab | G2894A | D877N | 10 | 13.70 |
| (n = 73) | ORF3a | G26167T | V259L | 9 | 12.33 |
| BA.1.15.1 | M | A26530G | D3G | 12 | 46.15 |
| (n = 26) | |||||
| BA.1.16.1 | ORF1ab | G1806A | G514E | 13 | 9.35 |
| (n = 139) | C6401T | P2046S | 18 | 12.95 | |
| M | A26530G | D3G | 127 | 91.37 | |
| N | G29162A | D297N | 4 | 2.88 | |
| C29274T | T334I | 4 | 2.88 | ||
| BA.1.17 | ORF1ab | T851C | Y196H | 15 | 3.98 |
| (n = 377) | C4113T | A1283V | 176 | 46.68 | |
| C5672T | P1803S | 156 | 41.38 | ||
| C10605T | P3447L | 12 | 3.18 | ||
| C12084T | T3940I | 13 | 3.45 | ||
| G15850A | D795N | 30 | 7.96 | ||
| M | A26530G | D3G | 322 | 85.41 | |
| N | G28436T | A55S | 5 | 1.33 | |
| BA.1.20 | ORF1ab | C15830T | A788V | 4 | 26.67 |
| (n = 15) | M | A26530G | D3G | 5 | 33.30 |
| BA.1.22 | ORF1ab | G11083T | L3606F | 7 | 7.87 |
| (n = 89) | C15928T | P821S | 6 | 6.74 | |
| N | C29466T | A398V | 7 | 7.87 |